Genomics & Precision Medicine

Authors: CDC Blogs Merline Feero, Marta Gwinn, and Muin J. Khoury, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, Georgia

Tracking the Scientific Literature on SARS-CoV-2 Variants Using the COVID-19 Genomics and Precision Health Knowledge Base

The first reports of SARS-CoV-2, the highly infectious virus causing COVID-19, swept across the globe in December 2019, prompting a burst of scientific activity. The rate of research and discovery intensified as the pandemic grew, resulting in a flood of publications in journals and on preprint servers around the world. More recently, SARS-CoV-2 variants have become a major focus of SARS-CoV-2 research in basic, clinical, and public health sciences.

CDC’s Office of Genomics and Precision Public Health established the COVID-19 Genomics and Precision Health (COVID-19 GPH) database to capture publications that reflect the influence of two broad emerging technologies: genomics (pathogen and human), and precision health (machine learning, artificial intelligence, and predictive analytics). Together, these fields are the leading edge of precision public health in COVID-19 and beyond. Data are continuously updated from PubMed, the NIH iSearch COVID-19 Portfolio, LitCovid, and media sources using an automatic retrieval and text mining strategy3 and manual curation by CDC staff.

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